Are any of the so-called anti-aging products on the market actually effective? Kevin sits down with two experts, Carolina Reis Oliveira and Alessandra Zonari from OneSkin to get the latest on the complex process of aging, senescent cells aka “zombie cells”, types of collagen and how collagen production is affected, the #1 offender of skin, how sugar plays a role in aging and much more. This episode is packed with all you need to know to uncover the truth about skin aging and learn how to take care of your skin for a healthier and younger-looking appearance.

Guest Bio and Links:
Carolina Reis Oliveira is the Co-founder and CEO of OneSkin, a biotechnology company dedicated to developing solutions that extend skin health and, thereby, longevity. With a biochemistry degree and a Ph.D. in Stem Cell Biology and Tissue Engineering, Carolina has led her team to innovate in the realm of skincare by tackling aging at its source. Her work not only encompasses scientific research but also bridges the gap between science and consumer skincare products. Carolina is an alumnus of IndieBio, the world's largest seed biotech accelerator. She moved from Latin America to Silicon Valley in 2016 to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.
Alessandra Zonari, co-founder of OneSkin, brings her expertise in immunology, stem cell biology, and bioinformatics to the forefront of the skincare industry. Her scientific acumen and dedication have been instrumental in the foundational research that led to the creation of OneSkin and its revolutionary products.
Listeners can learn more about OneSkin at https://www.oneskin.co/ 

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Resources:
Kevin's Newsletter: Join 100,000+ subscribers
Scientific Publications: OneSkin Publications
   
Show Notes: 

(0:00) Introduction

(1:00) Get 20% off at kevinrose.com/deleteme   

(3:00) Get $150 off at kevinrose.com/plunge   

(4:40) Overview of today’s episode 

(8:00) Introduction to skin health  

(10:30) The science of skin aging and senescent cells  

(13:00) Fasting and autophagy benefits   

(19:30) Join Kevin’s newsletter


(20:30) The role of sugar in aging 

(25:40) Collagen production and aging 

(29:00) How to spot an optimal vitamin C 

(36:30) Supplementation for skin 

(38:15) The start of OneSkin

(46:40) Scientific ways to measure wrinkles 

(53:40) OS-01 FACE Topical Supplement


(58:00) Probiotics and skin microbiome 

(58:30) Benefits of red light therapy 

(1:05:00) The latest on OneSkin 

(1:08:50) Common skincare myths  


Connect with Kevin:
Website: https://www.kevinrose.com/ 
Instagram - @KevinRose
X - @KevinRose
YouTube - @KevinRose

Carolina Reis Oliveira & Alessandra Zonari | OneSkin: Aging Myths, Senescent Cells, and How to Age Slower (#56)

Kevin Rose explores the forefronts of the AI, investment hacking, optimizing wellness, technology of the future, and the world's lastest cultural trends. Each episode is packed with valuable insights to fuel personal and professional growth, from technologists and scientists to zen masters and productivity hackers; this variety show will always provide you with an abundance of unconventional wisdom.

Kevin has been recognized as one of Time Magazine's 'Top 25 Most Influential People on the Web' and a 'Top 25 Angel Investor' by Bloomberg, highlighting his impact in the tech and investment spheres. His influence extends to the cover pages of prestigious publications like Businessweek, Red Herring, 7x7, and Inc. Magazine. Further highlighting his versatility and widespread recognition, Kevin has also made notable appearances on the Jimmy Fallon Show and Charlie Rose.

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Health & Fitness

Are you struggling with your health despite following all the "right" advice? The answer may lie in a surprising place: your metabolism. In this episode, Kevin sits down with Dr. Casey Means to explore the connection between metabolism and limitless health, and how understanding your unique metabolic needs can unlock your potential for optimal wellness. They discuss the latest research on metabolism and health, six biomarkers that predict metabolic disease, and practical tips for optimizing your metabolic function.

Guest Bio and Links:
Dr. Casey Means is a medical doctor, writer, tech entrepreneur (Levels Health), aspiring regenerative gardener, and outdoor enthusiast who lives in a state of awe for the miracle and mystery of existence and consciousness. During her training as a surgeon, Casey saw how broken and exploitative the healthcare system is and left to focus on how to keep people out of the operating room. Casey is passionate about working towards a healthier and happier planet by empowering people to understand their health and the limitless potential within.
Listeners can learn more about Dr. Casey Means at her website and on IG @drcaseyskitchen.

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Resources:
Kevin's Newsletter: Join 100,000+ subscribers
Dr. Casey Means Book: Good Energy: The Surprising Connection Between Metabolism and Limitless Health
Dr. Casey Means: Newsletter 
The Institute For Functional Medicine
Parsley Health
Osmia: Natural Skincare for Healthier, Happier Skin
The Way Meditation App
Hello Lingo: Your Personalized Metabolic Coach 

Show Notes: 

(0:00) Introduction

(1:00) Copilot: Get a 2-month free trial with code KEVINROSE at kevinrose.com/copilot


(2:15) Facet: $250 enrollment fee waived  

(4:00) Good Energy: The Surprising Connection Between Metabolism and Limitless Health


(4:20) Levels Health 

(5:30) The metabolic health crisis  

(11:15) Overview of metabolism   

(12:30) Question: How do you define metabolic dysfunction? 

(13:35) “Nothing could be scarier to the body than a cell that can't do its work.”


(14:50) The CDR: the cell danger response 

(14:55) Root causes of metabolic dysfunction

(17:35) “Every leading cause of death in the United States, other than suicide is fundamentally in some way related to the immune system being on overdrive all the time.” 


(22:30) LMNT: Electrolyte drink mix. Grab a free sample pack with code KEVINROSE 

(23:55) The Way Meditation App


(25:40) Question: is metabolic dysfunction a healthcare problem or an individual problem? 

(26:13) Core problems with the current healthcare system

(34:00) Hello Lingo - your personalized metabolic coach

(34:20) Upcoming healthcare trends 

(35:50) Six biomarkers that predict deadly diseases 

(37:20) What is ApoB testing 

(51:00) What is gamma-glutamyl transferase (GGT)   

(59:00) How to take back your health

(1:04:15) Potential dangers of glucose tolerance tests    

(1:07:45) Functional medicine doctors and how individuals can access relevant health tests

(1:09:30) What is homocysteine? 

(1:12:45) The barbaric truth about pollutants 

(1:18:25) Question: What are your thoughts on personal skincare items?

(1:23:50) “I think one of the easiest ways to get rid of the most toxins is simply to shop at the farmer's market..”


(1:31:30) Practical strategies and practical tips to get out of Good Energy 

(1:35:35) Question: What is the catalyst to take back control and make real change? 

(1:36:38) The connection between spirituality and health  


Connect with Kevin:
Website: www.kevinrose.com
Instagram: @KevinRose
X: @KevinRose
YouTube: @KevinRose

Good Energy: The Surprising Connection Between Metabolism and Limitless Health, Dr. Casey Means (#57)

Kevin is joined by Kevin Pereira and Gavin Purcell, hosts of ‘AI For Humans’ podcast to discuss all you need to know about the future of AI. They talk about the transformative potential of AI, the current state of the technology, and the challenges and opportunities that lie ahead. They also share their thoughts on the impact of AI on various industries and aspects of society, and offer some predictions for the future.

Guest Bio and Links:
Kevin Pereira is a television host, producer, and personality, recognized for his work on G4's "Attack of the Show!" With a passion for technology, gaming, and digital culture, Pereira has become a prominent figure in media, seamlessly blending entertainment with insightful discussions on tech trends. Beyond his hosting duties, Kevin is involved in podcasting, where he explores the intersections of technology and everyday life. His unique ability to demystify complex tech concepts while engaging a broad audience has solidified his status as a key voice in the digital age.
Gavin Purcell is an Emmy-winning showrunner, writer, & creative executive with a diverse background in media and technology. He’s known for his work on acclaimed productions like “The Tonight Show with Jimmy Fallon” & “I Love You America!” in addition to his work at Vox Media, G4TV, and numerous other outlets. In addition, he’s founded multiple companies in the emerging tech space, often infusing his media knowledge into new tech like Web3 or AI.
Kevin and Gavin co-host a podcast called AI For Humans where they demystify new AI technologies, highlight new tools & news for the AI-curious. 
Listeners can learn more about Kevin Pereira, Gavin Purcell, and AI For Humans at their website or on YouTube @AIForHumansShow.

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﻿Resources:
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Udio - AI music generator

Show Notes: 

(0:00) Introduction

(1:00) LMNT: Electrolyte drink mix with everything you need & nothing you don't. Get a free sample pack at kevinrose.com/lmnt 

(2:20) NordVPN: Huge discount + 4 months free on my favorite VPN 

(4:00) Kevin and Gavin introduce their history with technology and initial AI encounters

(6:30) The current state of AI  

(7:10) “Now is the worst this technology will ever be. It only gets better from here.” 

(9:30) The capabilities of GPT-3 and other models 

(17:30) Tools for AI music  

(21:30) Boston Dynamics robot  

(22:00) Figure 01


(24:00) Personalized financial planning. Get your $250 enrollment fee waived at kevinrose.com/facet


(26:00) Try Notion AI for free - kevinrose.com/notion  

(27:10) Using AI to create comedy and musical content 

(31:00) Install, run & control servers on your computer with 1 click - https://pinokio.computer/  

(39:00) Using AI to create character-driven content 

(48:00) The legal and ethical implications of AI

(50:00) Predictions for the future of AI

(55:30) Sora is an AI model that can create realistic and imaginative scenes from text

(1:09:30) AI For Humans Podcast  


Connect with Kevin:
Website: https://www.kevinrose.com/ 
Instagram - @KevinRose
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YouTube - @KevinRose

Gavin Purcell & Kevin Pereira, The Future of AI (#55)

Kevin sits down with Suneel Gupta CEO of RISE, a breakthrough wellness company to break down some of the key concepts in Suneel’s book, Everyday Dharma. Aside from the definition, origin and concepts of dharma, Suneel discusses how to achieve sustainable peak performance by embracing simple habits, how to bolster emotional resiliiance and engagement, and how to master psychological shifts required to overcome life setbacks.   
Once seen as the “face of failure” in the New York Times, Suneel Gupta understands the road to success is not always smooth. Learning from his mistakes, Suneel became the founding CEO of RISE, a breakthrough wellness company that partnered with First Lady Michelle Obama to deliver low-cost health coaching to people in need. He is now a visiting scholar at Harvard Medical School and host of an award-winning documentary series on Amazon Prime. He is also a bestselling author of Everyday Dharma, which is all about the timeless art of finding success and joy in what we do.
Listeners can learn more about Suneel at website https://www.suneelgupta.com/ on X @suneel and on IG @suneelgupta

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Mentions: 
Everyday Dharma Book: https://www.suneelgupta.com/
The ultimate cold plunge ice bath. Get $150 off at kevinrose.com/plunge
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Show Notes: 

(0:00) Introduction

(1:00) The ultimate cold plunge ice bath. Get $150 off at kevinrose.com/plunge


(2:30) Get two months of CoPilot FREE - kevinrose.com/copilot


(4:30) Shout out to Kevin for being one of the first to take a bet on RISE  

(5:30) What Rise is all about 

(11:55) “Authenticity has become everything. It’s no longer a factor, it’s a filter.” 

(15:30) Obama's 2004 keynote speech

(23:30) Shout out to the one and only Tim Ferris - https://tim.blog  

(25:00) DeleteMe: 20% off removing your personal info from the web  

(27:10) Suneel Gupta’s viral failure story 

(29:10) “Long term success can often come from short term embarrassment.”


(32:30) Suneel’s personal story on ‘how to win and how to lost’ 

(36:20) “I don’t lose. I either win or I learn.”  

(38:30) The arrival fallacy  

(43:30) The philosophy of dharma  

(50:00) Definition and origin of dharma 

(51:20) “As it turns out, when I go out and I unpack the Dharma stories, the people who really were able to find their way back to the center, it wasn't competence that got them there. It was curiosity.”


(1:02:00) The concept of rhythmic renewal 

(1:05:00) The 55-5 rule for work efficiency in productivity 

(1:27:00) Question: When you think about these trail heads that lead back to everyday dharma, what's a diversified person look like?

(1:30:00) The concept of seva: selfless service 

(1:36:00) Closing thoughts


Connect with Kevin:
Website: https://www.kevinrose.com/ 
Instagram - @KevinRose
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How to Cultivate Everyday Dharma, Suneel Gupta (#54)

Kevin is joined by Magatte Wade, renowned for her TEDTalk and activism dedicated to unlocking prosperity in Africa. Magatte discusses the challenges and opportunities facing Africa today. She elaborates on her journey since the talk, focusing on her efforts to improve Africa's economic conditions through innovative startup cities and advocating for economic freedom. Magatte provides a deep dive into the intricacies of creating prosperous environments in Africa, her personal experiences with bureaucratic challenges, and her vision for Africa’s future.

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Guest Bio and Links:
Magatte Wade is the world's leading African prosperity activist. She was made famous initially for a TEDTalk she made in 2017 about what she argues is an excessive regulatory environment in Africa which forces young Africans to emigrate for economic reasons. She is an entrepreneur, keynote speaker, and the author of The Heart of A Cheetah. 
Listeners can learn more about Magatte Wade at her website https://www.magattewade.com/, on X @magattew, and on YouTube @MagatteWadeOfficial

Resources:
Why it's too hard to start a business in Africa -- and how to change it
The Heart of a Cheetah 
Be the Solution: How Entrepreneurs and Conscious Capitalists Can Solve All the World's Problems by Michael Strong and John Mackey 
Africa Unchained: The Blueprint for Africa's Future by George Ayittey
Why Africa Needs Startup Cities

Show Notes: 

(0:00) Introduction

(0:50) Manscaped - Get 20% off with code KEVINROSE at manscaped.com


(2:30) Notion - Try Notion AI for free at kevinrose.com/notion


(4:20) Today’s guest is Magatte Wade

(6:50) Why it's too hard to start a business in Africa -- and how to change it 


(12:00) Slavery in the 21st century  

(14:50) Reasons Africa has been one of the fastest at adopting cryptocurrency and bitcoin   

(17:00) What makes money ‘sound’

(19:55) Facet: The Future of Financial Planning - www.facet.com/kevinrose    

(22:10) Question: What do you need to have happen so that rather than leaving Africa, there can be places in Africa that are entrepreneurial hubs that have true prosperity? 

(27:00) “How come some countries like mine are poor while others are rich?” 

(27:15) Stereotypes surrounding the African economy  

(30:40) Magatte’s journey into entrepreneurship  

(36:00) “You were always raised to criticize by creating. Got a problem with this? What's your solution? It doesn't have to be the right one, but get on that journey of solving.” 


(45:15) Question: Where do you feel you are going to have the most impact in your mission? 

(46:15) The Heart of a Cheetah  

(47:30) Magatte discusses the conflicting African ideologies  

(51:10) Question: Is it going to take a series of iterative changes or a revolution to have Africa prosper? 

(57:30) The concept of startup cities in Africa 

(59:00) The British common law explained - Dubai being the example 

(1:07:35) Próspera | Maximize Human Prosperity

(1:19:00) Partners in Próspera 


(1:23:00) Inspirations, mentors, and closing thoughts


Connect with Kevin:
Website: https://www.kevinrose.com/ 
Instagram - @KevinRose
X - @KevinRose
YouTube - @KevinRose

Carolina Reis Oliveira & Alessandra Zonari | OneSkin: Aging Myths, Senescent Cells, and How to Age Slower (#56)

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